除了开头要提到的基本信息（如编辑姓名，期刊名字，论文标题，Manuscript ID）之外，这个部分还需要总的表达一下对编辑和审稿人的感谢，表示已经解决了审稿人提出来的所有问题与建议，并表明下文回复审稿人意见的格式（加粗/斜体/字体颜色）。在感谢部分要注意的是，尽量不要说例如“Thank you for your comments, which have helped us to substantially/greatly improve the manuscript.” 的话，评论稿件质量是审稿人的工作，不要冒昧地夸赞自己做出的修改。
We appreciate all of the valuable comments from the reviewers of our work. We have revised our manuscript, according to the reviewers’ comments, questions, and suggestions.
We highly appreciate the reviewers for their insightful comments and criticism, which have helped us improve both the content and the presentation of our work. We believe that the revised version of our paper addresses all concerns by the referees in detail.
We greatly appreciate the thorough and thoughtful comments provided on our submitted article. We made sure that each one of the reviewer comments has been addressed carefully and the paper is revised accordingly.
In what follows the referees’ comments are in black and the authors’ responses are in red.
We have incorporated most of the suggestions made by the reviewers. Those changes are highlighted within the manuscript.[修改的部分高亮] Please see below, in blue, for a point-by-point response to the reviewers’ comments and concerns. [回复的部分用蓝色字体]
We made three notable changes to the manuscript,…
Responses to the comments of Reviewer #1
Responses to the comments of Reviewer #2
值得注意的是，Response letter是发给编辑看的，虽然其他审稿人也能看见你的Peer Review File，但还是应该在回复的过程中使用第三人称提及审稿人，如“We agree with the reviewer”而不是“We agree with You”。
We have added a comment in the section “…” to point out the…
we have inserted two new figures to provide clear illustration of…
We added the two references and commented on them in Section 6.2.4 and Section 6.5.
These references have been added and discussed in the paper — Sections 6.2.4 and 6.5.1
The paper is checked again to improve its Grammar.
The said sentence is rephrased to make the sentence easy to understand
We have corrected the grammatical issues pointed out in the manuscript and accompanying figures and tables;
The suggested key terms have been used throughout the manuscript.
We mentioned there were 45 samples in total in the Methods (page 6, line 4), but we have now also added the following to the start of the Results section to avoid any potential confusion: ‘Of the 45 samples tested, 9…’ (page 8, lines 19-20).
There were 15 samples in each of the 3 groups (Methods, page 3, line 20). We have reworded the text to state the total of 45 samples explicitly.
The total sample number was 45, as mentioned in Table 1. We have now added this to the main text for clarity (Procedure, page 3, line 7).
We have mentioned the limitations in the paper. To reiterate(重复一下), …
[提出冲突的地方]Reviewer 1 suggests that…,Reviewer 2, on the other hand, would like to see…
[提出你的看法]We considered…,so we are eager to know your perspective on the matter.
[两个版本都可以提供] In fact, we tried the revisions that way at first and would be happy to send that version along as well if it might be helpful.
While we appreciate the reviewer’s feedback, we respectfully disagree. We think this study makes a valuable contribution to the field because [描述您的研究或其结果所获得的知识、提供的见解、回答的问题等].
对于增加实验，你可以揣摩审稿人的态度的强硬，并考虑其他审稿人的好评程度，编辑的倾向性。如果总体比较乐观，其他审稿人和编辑也倾向于修，那么尽量小补实验 + 增加一些思路上的分析。如果总体意见不太乐观，编辑也不太看好本文，那么还是要尽全力补充实验，毕竟补了后发表机会会更大些。
可以使用这些关键词：”follow-up study,” “future research/consideration,” “new direction,” “outside the scope of the study this time,” “We agree …, but we prefer to focus on,”
We would also be interested in the effect on xxx. The data that we have cannot reveal this, but our protocols could be modified for a follow-up study.
We agree that the effect on xxx is an important line of study. We have now acknowledged this and suggested it as a topic for further research in the Discussion section of the revised manuscript (page 12, lines 24–29).
We agree that the effect on xxx would be interesting to know. Our study was designed to focus specifically on xxx this time and we’d like to keep the focus intact, but we have included your point as a consideration for future study (page 15, lines 9–12). Thank you for the suggestion.
[指出困难]There is a number of complications/ It clearly goes beyond the state of the art. （超出了技术水平）, which prevent a further and more detailed analysis of these processes within the scope of this manuscript.
可以使用这些关键词：”clarify”, “ambiguity”, “could be understood in this way,” “Thank you for pointing out the potential for misunderstanding”
Several statements that we made were more ambiguous than intended, and we have adjusted the text to be clearer.
Thank you for pointing out that our statement could be understood in this way. We did not mean that the results apply to all computers but only to single-core computers. We have clarified the explanation in Section 2 to highlight why our results are limited to single-core computers.
Our data do not support the statement that our results apply to all computers at this stage. To avoid potential misunderstanding, we have reworded our hypothesis statement to focus on single-core computers only.
We have reworded the text to state the scope of our research was focused on single-core computers, rather than all computers. Thank you for pointing out the ambiguity of our statement.
We mostly agree. Where we differ is with the idea that there is nothing wrong with the risk factor approach. As we describe in the paper,
注意信的结尾，像 “Since all the corrections have been made, we hope the manuscript will now be accepted without any further changes” 这样的结尾可能会过于自负。
我们可以这么说：“We look forward to hearing from you regarding our submission. We would be glad to respond to any further questions and comments that you may have”，这样的结尾有礼貌也表达了愿意在必要的情况下进行更多修改的意愿。
有的期刊部分文章，如PeerJ(https://peerj.com/reviews/)，nature research的Supplementary information里的Peer Review File都有公开同行评议的过程，大家可以进一步了解审稿人问了什么问题，作者是如何回复的。